Chemical Technology Processes in API Manufacturing (PME/ME/CHE538)

A broad overview of bulk active pharmaceutical ingredient manufacturing and unit operations. Cover the basics of process scale-up and transport processes, including mass, heat, and momentum transfer. Explore process synthesis, analysis, and design. Familiarize yourself with traditional separation processes, including distillation, evaporation, extraction, crystallization, and absorption. Find out about new separation processes, including pressure swing adsorption, molecular sieves, ion exchange, and reverse osmosis. Study micro-filtration, nano-filtration, ultra-filtration, and dia-filtration. Gain knowledge of gas permeation, pervaporation, supercritical fluid extraction, and high performance liquid chromatography (HPLC). Review batch and continuous reactors for homogeneous, heterogeneous, catalytic, and non-catalytic reactions.